| Alivia Cleveland - Fort Mill | 18:12.50 | 18:29.70 | ( 17.20 ) |
| Laura Perry - Philip Simmons | 18:41.90 | 18:54.50 | ( 12.60 ) |
| Avery Belk - James Island | 18:56.20 | 18:35.90 | 20.30 |
| Avah Mallek - Philip Simmons | 19:08.20 | 18:42.00 | 26.20 |
| Annabel Martin - Heathwood Hall | 19:10.80 | 19:57.90 | ( 47.10 ) |
| Nora Brahim - Bishop England | 19:14.20 | 19:12.90 | 1.30 |
| Kaylee Rovenstine - Fort Mill | 19:22.90 | 19:33.80 | ( 10.90 ) |
| Avery Moriarty - Fort Mill | 19:39.50 | 20:09.40 | ( 29.90 ) |
| Georgia Babcock - Chapin | 19:44.40 | 19:59.50 | ( 15.10 ) |
| Lauren Kelly - Riverside | 19:46.20 | 20:24.90 | ( 38.70 ) |
| Caroline King - J.L. Mann | 19:56.50 | 19:14.20 | 42.30 |
| Lydia Smith - Heathwood Hall | 20:01.90 | 20:06.20 | ( 4.30 ) |
| Kaylanna Burroughs - West Florence | 20:02.60 | 19:18.90 | 43.70 |
| Haley Ruth - Dorman | 20:06.90 | 20:42.20 | ( 35.30 ) |
| Dorothy Hutchins - Heathwood Hall | 20:10.30 | 18:51.70 | 1:18.60 |
| Mia Zook - Fort Mill | 20:11.40 | 19:44.60 | 26.80 |
| Keziah Varner - Philip Simmons | 20:11.70 | 20:26.90 | ( 15.20 ) |
| Eliza Roy - C... |