| Ava Lindsey - Greenville Hurricanes | 18:33.74 | 18:08.01 | 25.73 |
| Daya Ross - Wren | 18:34.73 | 18:25.98 | 8.75 |
| Alivia Cleveland - Fort Mill | 18:35.12 | 18:45.75 | ( 10.63 ) |
| Nora Brahim - Bishop England | 18:44.99 | 19:03.72 | ( 18.73 ) |
| Anna Kelly - Blythewood | 18:47.90 | 18:54.11 | ( 6.21 ) |
| Ella Nighbor - Clover | 18:51.48 | 17:55.12 | 56.36 |
| Kaylee Rovenstine - Fort Mill | 19:05.66 | 18:34.33 | 31.33 |
| Caroline King - J.L. Mann | 19:10.50 | 20:41.55 | ( 1:31.05 ) |
| Avery Griffith - Mauldin | 19:15.82 | 18:57.11 | 18.71 |
| Anna Cavallon - Wando | 19:17.27 | 18:57.35 | 19.92 |
| Kylee Mast - Greenville | 19:19.89 | 20:30.70 | ( 1:10.81 ) |
| Elloree Flippin - Spartanburg | 19:22.07 | 19:00.47 | 21.60 |
| Dorothy Hutchins - Heathwood Hall | 19:22.09 | 20:37.69 | ( 1:15.60 ) |
| Avah Mallek - Philip Simmons | 19:26.93 | 19:05.68 | 21.25 |
| Jayda Dyke - Mauldin | 19:31.82 | 19:11.33 | 20.49 |
| Lowndes Smith - Greer Middle College Charter | 19:35.98 | 20:50.25 | ( 1:14.27 ) |
| Corrie Reinhardt - North Charleston | 19:39.77 | 19:20... |
